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Removal of the implant may be very difficult or impossible if the implant is not where it should be.

If this happens, you may become pregnant. The implant may not be placed in your arm at all due to failed insertion. You may need special tests to check that the implant is in place or to help find the implant when it is time to take it out.

If you cannot feel the NEXPLANON implant, contact your healthcare provider immediately and use a non-hormonal birth control method (such as condoms) until your healthcare provider confirms that the implant is in place. Immediately after the NEXPLANON implant has been placed, you and your healthcare provider should check that the implant is in your arm by feeling for it. These medicines will be used when the implant is placed into or removed from your arm. Talk to your healthcare provider about using NEXPLANON if you have diabetes, high cholesterol or triglycerides, headaches, gallbladder or kidney problems, history of depressed mood, high blood pressure, allergy to numbing medicines (anesthetics) or medicines used to clean your skin (antiseptics). You should not use NEXPLANON if you are pregnant or think you may be pregnant have or have had blood clots have liver disease or a liver tumor have unexplained vaginal bleeding have breast cancer or any other cancer that is sensitive to progestin (a female hormone), now or in the past or are allergic to anything in NEXPLANON.